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One year ago this month, the Food and Drug Administration (FDA) issued a black box warning on a common type of laxative known as oral sodium phosphate, or OSP, available both over-the-counter and by prescription. After years of investigation, the FDA finally alerted health care providers and the public of the risk of a serious kidney injury known as acute phosphate nephropathy associated with the use of OSPs.
Let’s face it. There is no comfortable way to prepare for a colonoscopy. You can call it a necessary evil, but colon screenings are necessary for early detection of colorectal cancer for people ages 50 and older, those with a family history, or individuals who are experiencing bothersome symptoms, such as blood in the stool. After all, early detection of precancerous lesions are associated with an up to 90 percent reduction in colon cancer, the country’s second-leading cause of cancer deaths.
Attorney Russell Todd Abney with Beasley Allen Law Firm has filed a lawsuit against C.B. Fleet Company, Inc., on behalf of Mary Little, a resident of Newton County, Georgia, claiming that the plaintiff suffered severe personal injuries as a result of ingesting Fleet’s over-the-counter product known as Fleet Phospho-soda.
One of the hottest topics in nephrology over the past few years has been the epidemiologic and histopathologic studies that suggest a link between oral sodium phosphate (OSP) colonoscopy preparations and a serious form of kidney injury known as acute phosphate nephrology, according to The Renal Fellow Network.
As more cases of the condition were reported to the Food and Drug Administration (FDA), the agency last December issued a black box warning on prescription brands of OSP, such as Visicol and Osmo Prep. C.B. Fleet, makers of over-the-counter OSPs, also pulled their products from store shelves. While the Fleet products were deemed safe when taken in low doses as a laxative, Fleet had recommended doctors to tell their patients to use the over-the-counter OSPs in higher doses to prep the bowel prior to colonoscopies.
The American Society of Nephrology (ASN), a group that leads the fight against kidney disease in the U.S., holds its annual meeting and scientific exposition next week as part of ASN Renal Week, October 27 – November 1, 2009. The national Renal Week was originally formed as a way to disseminate information on new advances in the science of nephrology. Since then, the educational activities have greatly expanded to meet the needs of both practicing nephrologists and renal scientists.
Movie stars and celebrities may swear by them, but medical experts agree that colon cleansing should only be done when medically necessary.
“Sometimes it is necessary for people preparing to undergo a medical procedure or examination, such as a colonoscopy or a colon x-ray,” says to Dr. Mark Larson, a gastroenterologist at Mayo Clinic in Rochester, Minn., in the Hartford Courant. “But unless a doctor has recommended it as a preparation for such procedure, I strongly discourage people from colon cleansing. It can cause traumatic injury to the colon and result in long-term medical problems.”
Most people dread colonoscopies. Not only does the procedure, which involves a physician running a flexible tube through your colon and intestines, sound uncomfortable, the prep can be a real pain in the you-know-what. This is one reason why, when your doctor orders a colonoscopy, you’ll want to be sure you cleanse your bowel thoroughly and effectively to ensure that your doctor has a clear view of your colon. If not, you may have to repeat the procedure and the prep along with it.
To hear your doctor recommend a “colonoscopy” can send chills down most peoples’ spines. The procedure, which involves a doctor sending a little camera fixed to the end of a flexible tube through the colon and into the intestines, can make even the strongest folks a bit uncomfortable. Some even fear that the procedure itself can cause harm. One study hopes to put those fears into perspective.
Many physicians who perform colonoscopies are beginning to ask their patient for a second cleansing of the bowel in the wee hours before their procedures to ensure the bowel is clean and reduce the need for a redo.
A study by a group of Italian researchers shows that virtual colonoscopies that use computer tomography scans are almost as effective at detecting tumors and precancerous lesions as standard colonoscopies, which requires threading a camera through the colon. The study, published in The Journal of the American Medical Association, suggests that the new procedure may offer an alternative to people who are too embarrassed or afraid to undergo a standard colonoscopy.
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