News Tagged ‘acute phosphate nephropathy

Some detox practices carry serious risks

It seems every time you turn on the TV, flip through a magazine, or go online, you are faced with another commercial or infomercial about the benefits of detoxifying the body through magic pills or solutions. From detox diets and foot cleansings to nasal irrigation and colon clearing– the options are seemingly limitless. Proving the benefits of such toxin-removing practices is sketchy, says Dr. Tyrone M. in a column in the Phillippine Star. And some practices can be downright dangerous to your health.

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Stool sampling may detect gastrointestinal cancers early

Could samples of your stool keep you from having a colonoscopy? Researchers at Baylor Medical Center think so. A team of doctors from Baylor pored through stool samples, analyzed long strands of DNA and were able to diagnose gastrointestinal cancers early, according to a report from KARE-TV 11.

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Humor takes the anxiety out of colonoscopies

Colonoscopies are serious business. The procedure involves sending a small camera inside the colon to search for abnormalities, including colon or rectal cancers, also known as colorectal cancer. Regular colon screenings can find polyps even before they become cancerous. By removing those polyps, one can literally dodge colorectal cancer.

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Canada orders makers of common OTC laxatives to re-label

OSP products incl fleet 150x120 Canada orders makers of common OTC laxatives to re label Health Canada has ordered manufacturers of over-the-counter oral sodium phosphates (OSP), such as Fleet Phospho-Soda, to either re-label the products to remove any mention of bowel cleansing, or remove the products completely from the Canadian market.

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Elderly at greater risk of complications following colonoscopy

The elderly and those with certain chronic health conditions are at greater risk of suffering from complications following colonoscopies, according to a study conducted by researchers from National Cancer Institute and the University of North Carolina. The study, which was published last month in the Annals of Internal Medicine, looked at data from 53,220 Medicare beneficiaries aged 66 to 95 who underwent colonoscopy between 2001 and 2005.

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Severe kidney injury linked to use of OSP products

fda logo 150x150 Severe kidney injury linked to use of OSP productsOn December 11, 2008, the Food and Drug Administration (FDA) issued a safety alert calling for a black box warning on prescription oral sodium phosphate (OSP) products used to prepare the bowel prior to colonoscopies following reports of a serious form of kidney injury in patients who had taken OSP products.

The black box warning fell on Salix  Pharmaceuticals’ prescription OSP brands Visicol and Osmo Prep, and serious warning was placed on over-the-counter OSP products such as Fleet Phospho-soda and Fleet Accu-Prep. The serious adverse event that was occurring in patients repeatedly over the years was a serious form of kidney injury now known as acute phosphate nephropathy.

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Recalled over-the-counter OSP products still on shelves in Jamaica

fleet phospho soda package 454 144x150 Recalled over the counter OSP products still on shelves in JamaicaWhen the Food and Drug Administration (FDA) issued a black box warning on prescription oral sodium phosphates (OSP) Visicol and Osmo Prep, medications used to clear the bowel before colonoscopies and other procedures, C.B. Fleet also removed its over-the-counter OSP solutions from store shelves. While safe when used in low doses as a laxative, those products, known over-the-counter by such brand names as Fleet Phospho-soda and Fleet Accu-Prep, when used in higher doses for bowel cleansing, have been linked to a serious form kidney injury called acute phosphate nephropathy. Despite the warnings issued here in the U.S., the products are still widely available in countries like Jamaica.

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Thousands could be injured each year by OSP bowel cleansers

Two studies in the Journal of the American Society of Nephrology (JASN) suggest that at least 50 percent of patients undergoing a screening colonoscopy receive oral sodium phosphates (OSP) to prep their bowel. Which means as many as 7 million of the 14 million Americans who have regular screenings each year are at risk for a serious kidney injury that has been associated with the use of OSP. The article estimates that as many as 1,400 to 7,000 people could be injured each year by the product used routinely for bowel clearing.

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Colon hydration offers alternative to OSP for bowel prep

Some hospitals across the country are choosing an alternative method of prepping the bowel before colonoscopies that does not require patients to drink a gallon of liquid laxatives the day before the procedure, according to EndoNurse. The new procedure is called colon hydrotherapy and involves infusing the colon with warm, filtered, chemical-free water to effectively clear it.

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Some may not realize OSP caused kidney injury

fleet phospho soda package 454 144x150 Some may not realize OSP caused kidney injurySome people who suffer from kidney problems may not realize their condition may be linked to products used to cleanse the bowel before medical procedures like colonoscopies, says Ben Locklar, shareholder with Beasley Allen Law Firm. It wasn’t until around 2005 that doctors began making the connection between oral sodium phosphate (OSP) products and a serious kidney injury known as acute phosphate nephropathy. Since then, more and more cases have been reported and hundreds of lawsuits have ensued.

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